The 47-year-old man was struck at the intersection of E. Palisade and Sylvan avenues at 10:50 a.m., Englewood Police Detective Lt. Ronald Waldt said.
Officers administered aid until EMTs and paramedics arrived. The cyclist was taken to Englewood Hospital. The 34-year-old Mercedes Sprinter van operator remained on scene.
The intersection is a busy one and the route a popular one among cyclists, who often ride along Route 9W toward Rockland County.
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Police were expected to release further information at a later time.
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